alexa Abstract | Brain Tumors with Review of Literature: Immunohistochemistry or Biomarkers Versus Histomorphology

Neuro-Oncology: Open Access
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access


Brain tumors show genetic heterogeneity and various immunohistochemical / biomarkers are now available for brain tumor diagnosis in addition to the advanced molecular techniques. However the basic routine histopathology remains the gold standard for diagnosis corroborating with the characteristic radiology and immunohistochemistry to substantiate or confirm diagnosis and MIB1/Ki67 for grading of tumors. A total of 150 brain tumors were retrospectively analyzed in this study. The histopathology was correlated with immunohistochemical findings to note the difference in result and correlate the histology with immunohistochemistry. Out of total 150 patients, 65 were males and 45 were females. Out of the 150 brain tumors, 37 were glial tumors in which there were 05 grade 1 astrocytoma out which one was protoplasmic astro-cytoma, 01 grade 2 astrocytoma 05 anaplastic astrocytoma. 02 oligodendroglioma, 30 glioblastoma multi-forme and one was gemistocytic glioblastoma, 02 mediastinal seminoma in young males of average age 25 years, 46 meningiomas of which 30 were transitional type and 20 fibroblastic, 19 pituitary adenomas, 01 mediastinal germ cell tumor, 10 ependymomas of which 01 was myxopapillary type and 01 anaplastic type, 06 hemangioblastomas, 03 medulloblastoma, 01 atypical teratoid rhabdoid Tumor, 10 raniopharyngiomas, 02 cavernous angiomas, 05 neurocytomas, 01 adenocarcinoma deposits, 01 case of Tuberculosis. Immunohistochemistry with relevant antibody markers were performed for confirmation of diagnosis, differentiation of the tumors and MIB1 for grading of tumors. In some CNS tumors immunohistochemistry is useful but IHC panel can substantiate histopathology to grade and prognosticate the brain tumors but histopathology remains gold standard.

Author(s): Tanushri Mukherjee Rajat Dutta Joydeep Ghosh and Manish Sharma


Glioblastoma multiforme, Ependymoma, Tumors, Immunohistochemistry, Tomography, Oxidation, Astrocytomas, Brain tumor, Glioma, Glioblastoma multiforme (GBM)

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

1-702-714-7001Extn: 9037

Business & Management Journals


1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version