alexa Abstract | Breast carcinoma in pregnancy and lactation: A diagnostic and therapeutic dilemma

International Journal of Collaborative Research on Internal Medicine & Public Health
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)


Objective: To study the clinical presentation, pathological features, receptors type, and reason for the delay of diagnosis of breast carcinoma during pregnancy and lactation.

Patients and methods: This is retrospective study of patients with pregnancy associated breast carcinoma (PABC), treated at our hospital from 2003 to 2009.

Results: Of the 16 patients, 8 (50%) were pregnant and 8 (50%) were lactating with an average age of 30years (range, 21 to 41years). Four (25%) underwent therapeutic abortions, two (12.5%) cesarean section, one (6.25%) patient had spontaneous abortions and one (6.25%) had no follow up. Fifteen (94%) presented with a breast mass, 37.5% with nipple retraction and 31% presented with inflammatory changes in the breast. Symptoms and signs were overlooked by physicians in 8 (50%) of patients, resulting in delay of referral. In 5 (31.25%) the delay was due to patients' fear of cancer and only 3 (18.75%) there was no delay. The majority of cases were ductal 12 (75%). Only one-third presented with early stage, the rest with advanced stage. Half (50%) were Estrogen receptor and Progesterone receptor (ER, PR) negative, while 6 (37.5%) were positive. Human epidermal growth factor receptors type2 (HER2) positivity was found in 3 (18.75%) while 2 (12.5%) were ER negative but PR positive.

Conclusion: Breast masses during pregnancy and lactation is not always benign. It may be overlooked and all appropriate methods should be used to role out breast carcinoma.

To read the full article Peer-reviewed Article PDF image

Author(s): Ali M AlAmri


Carcinoma, pregnancy, lactation, breast

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version