alexa Abstract | Chemcial oxygen demand reduction of Aqueous Active Pharmaceutical Ingredient - Furosemide waste water streams using Advanced Oxidation- Fenton process based on H2O2/Fe+2 salt

Der Pharmacia Sinica
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Research Article Open Access


Active Pharmaceutical Intermediates in waste waters is emerging contaminants in the aquatic environment because of their adverse effect on aquatic life and Environment. The API have high COD value and low BOD3 and hence difficult to treat biologically. In this study, advanced oxidation processes (AOPs) utilizing the H2O2/Fe+2, Fenton, reactions were investigated in labscale experiments for the degradation of Furosemide containing waste water streams. The experimental results showed that the Fenton process using H2O2/Fe+2 was the most effective treatment process. With Fenton processes, COD Reduction of wastewater can be achieved successfully. It is suggested that Fenton processes are viable techniques for the degradation of Furosemide from the Waste water stream with relatively low toxicity of the by-products in the effluent which can be easily biodegradable in the activated sludge process, and other less degraded streams with high total dissolved solids can be taken to multiple effect evaporator or Reverse osmosis. In addition, study the degradation of Furosemide by advanced oxidation Fenton process under optimum conditions. The Fenton process with H2O2/Fe+2 is considered a suitable pretreatment method to degrade the Active pharmaceutical molecules and improve the biodegrability of the waste water.

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Author(s): Sayyed Hussain Shahid Shaikh and Mazahar Farooqui


COD reduction, Fenton Process, Advanced Oxidation Process

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