alexa Abstract | Clinical Evaluation on Treatment of Oral Lichen Planus with Yiqiyangyin Mixture and Its Mechanism

Electronic Journal of Biology
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Abstract

To observe the clinical effects of Chinese herbal medicine Yiqiyangyin Mixture on oral lichen planus (OLP) and to explore its mechanism, we randomly selected two groups of newly diagnosed patients, they were treated with Yiqiyangyin Mixture and total glucosides of paeony(TGP), respectively, for three months, and the clinical effects of the two treatment system were compared by using semi-quantitative REU scoring system; and the changes of NF-κB-dependent inflammatory medium TNF-α, IL-1β, IL-6, IL-8 and TH1/TH2 representative cytokines IFN-γ, IL-10 levels were also observed before and after treatment. The overall effective rates on OLP were no significant difference between trial group and control group, but the therapeutic effect of Yiqiyangyin Mixture on the erosive OLP was more significant, its subjective symptoms and objective signs were all evidently improved, and compared with the TGP group, P <0.05; the changes of NF-κB-dependent inflammatory mediators TNF-α, IL-8 and TH1/TH2 representative cytokine IL-10 were significantly before and after treatment (P < 0.05). It shows that Chinese herbal medicine Yiqiyangyin Mixture is effective for treatment of OLP, especially the effect on erosive OLP is more significant, and the prescription may plays a role through regulating Th1/Th2 immune balance and blocking activation of NF-κB information pathway.

To read the full article Peer-reviewed Article PDF image

Author(s): Xiaobing Guan Jingping Bai Jie Fu Huina Zhang Lihua Wang Ping Li

Keywords

oral lichen planus, Chinese herbal medicine Yiqiyangyin Mixture, NF-κB dependent cytokines, TH1/TH2 cytokines.

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords