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Research Article Open Access
Our objective is to clinically validate two different pharmacoeconomics models for treating Dupuytren’s contracture (DC). We conducted a cross-sectional study to learn about orthopedists’ preferences regarding treatment for DC. A guided interview on two possible decision trees for treating DC was used. The attributes considered were: structural difficulty, comprehensibility, adaptability, reliability, extrapolation and applicability. The questionnaire was answered by 27 surgeons. The difference total score obtained was not statistically significant (t=1.523; P=0.14). No floor or ceiling affect was observed. The standard error of measurement was calculated at 0.796, being 8.0% with respect to the global for the scale. Minimal detectable change was 2.21. The total Cronbach’s alfa was high for both Models. The result of the principal analysis of the components explained 82.5% of the variation. Clinical validation of a pharmacoeconomic model for the management of DC has been shown to be feasible, flexible, and economical.
DupuytrenÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂ¢ÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂs contracture, validity, pharmacoeconomic models, Delphi method, collagenase Clostridium histolyticum, Clinical Validation of Pharmacoeconomic Models in Dupuytren?s Contracture