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Short Communication Open Access
Shade dried, powdered seeds of Sterculia guttata were extracted using a Soxhlet extractor with ethanol. Ethanol was removed under reduced pressure and dried to obtained crude extract. This extract was evaluated for its effect on behavioral changes, exploratory activity and barbiturate-sleeping time, using appropriate standard methods in mice. The extract exhibited dose-dependent CNS depressant activity.
Barbitone sodium, CNS depressant activity, pentobarbitone sodium, Sterculia guttata Roxb., Swiss albino mice