alexa Abstract | CNS depressant activity of ethanol extract of <i>Sterculia guttata</i> seeds in mice

Indian Journal of Pharmaceutical Sciences
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Shade dried, powdered seeds of Sterculia guttata were extracted using a Soxhlet extractor with ethanol. Ethanol was removed under reduced pressure and dried to obtained crude extract. This extract was evaluated for its effect on behavioral changes, exploratory activity and barbiturate-sleeping time, using appropriate standard methods in mice. The extract exhibited dose-dependent CNS depressant activity.

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Author(s): SR Katade AV Misar AM Mujumdar UD Phalgune RD Wakharkar NR Deshpande


Barbitone sodium, CNS depressant activity, pentobarbitone sodium, Sterculia guttata Roxb., Swiss albino mice

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