alexa Abstract | Comparative Anthelmintic Activity of Aqueous and Ethanolic Leaf Extracts Of Clitoria Ternatea

International Journal of Drug Development and Research
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Abstract

The present study aimed at the in-vitro comparative study of anthelmintic activity of aqueous and ethanolic extracts of leaves of Clitoria ternatea using Eisenia foetida at three different concentrations (100, 50, 25 mg/ml) respectively. The study involved the determination of time of paralysis (P) and time of death (D) of the worms. At the concentration of 100 mg/ml both the ethanolic and the aqueous extracts showed very significant activities as compared to the standard drug levamisole (0.55 mg/ml). In case of aqueous extract the time of paralysis and death time was observed as 18 ± 1.57 and 53.33 ± 0.33 and in case of ethanolic extracts 12.33 ± 0.80 and 32.33 ± 0.71 respectively. In conclusion, the use of leaves of Clitoria ternatea as an anthelmintic have been confirmed and further studies are suggested to isolate the active principles responsible for the activity

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Author(s): Manoj Salhan Bimlesh Kumar Prashant Tiwari Pardeep Sharma Harleen Kaur Sandhar Mayur Gautam

Keywords

Clitoria ternatea, Anthelmintic, Eisenia foetida, Levamisole

 
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