alexa Abstract | Comparative anti anemic activity of Azadirachta indica leaves and its combination with Emblica officinalis in phenyl hydrazine induced anemia using rats

Journal of Chemical and Pharmaceutical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Original Articles Open Access


Azadirachta indica (neem leaves) and its combination with Emblica officinalis (amla) were evaluated for their antianemic activity in phenyl hydrazine induced anaemic animals. Rats were divided into 7 groups of 6 each. Group 1 was given normal saline and served as control and all other groups were given 60 mg/kg b.w of phenyl hydrazine for 2 days to induce anemia. Group 2 served as positive control (only treated with phenyl hydrazine) and Group 3 was treated with standard ferrous sulfate containing drug Fefol®(0.012mg/kg,p.o.) and served as standard .Group 4 and 5 were treated with different doses (200 and 400 mg/kg b.w.) of aqueous extracts of Azadirachta indica leaves respectively. Whereas Group 6 and 7 were treated with combination of aqueous extract of Azadirachta indica leaves and Emblica officinalis fruit (200 and 400 mg/kg b.w.) respectively. All the treatments were given orally and continued up to 14 days. On 15th day blood samples were collected by retroorbital puncture and hematological parameters such as haemoglobin (Hb) concentration, RBC count and WBC count were estimated. Results showed that both Azadirachta indica leaves and its combination with Emblica officinalis fruit showed significant anti anemic activity but compared to Azadirachta indica leaf extract alone, its combination with amla showed better activity. This synergistic action of plants may be due to increase in absorption of iron from neem leaves due to vitamin C in amla fruit and this combination may be an alternative to synthetic iron therapy in anemia.

To read the full article Peer-reviewed Article PDF image

Author(s): Vamsee Veena A Jyothi Y Rina Pokhrel Rajdwip Ghosh Ronak Patidhar and Vijay Yadav


Phenyl hydrazine, anaemia, Azadirachta indica, Emblica officinalis, haematological parameters, anemia

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

1-702-714-7001Extn: 9037

Business & Management Journals


1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version