alexa Abstract | Comparative Conventional and Microwave assisted synthesis of some pyrazoline derivatives and their antimicrobial activity

Journal of Chemical and Pharmaceutical Research
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Abstract

A novel and simple method have been developed for the synthesis of some Pyrazoline derivatives under microwave irradiation. In addition, these compounds were obtained with conventional heating procedures to compare them with those obtained with microwave irradiation. All the compounds synthesized were characterized by running TLC, Elemental analysis, IR, NMR and MS spectra. Consequently, the microwave irradiation method provided nearly the same or higher product yields in a very short period of time. These results suggest that the microwave irradiation method was more useful than the conventional method due to shorter reaction time and energy savings.

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Author(s): Bharat Parashar Sudhir Bhardwaj Sharda Sharma G D Gupta V K Sharma andP B Punjabi

Keywords

Synthesis, microwave irradiation, conventional heating Isonicotinohydrazide, ethyl 2-cyanoacetate, hexane-2, 4-dione.

 
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