alexa Abstract | Comparative Evaluation of Hepatoprotective Potential of roots of Blue and white flowered varieties of Clitoria ternatea Linn

Der Pharmacia Sinica
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access


Pet Ether, Chloroform, and Methanol extracts of roots of Blue and White flowered varieties of Clitoria ternatea (CT) were studied for their hepatoprotective potential against carbon tetrachloride (CCl4) induced hepatotoxicity in rats. The hepatoprotective activity was assessed using various biochemical parameters like serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), serum alkaline phosphatase (ALP) and total bilirubin along with histopathological studies of liver tissues. The substantially elevated serum enzymatic levels of serum transaminases, alkaline phosphatase and total bilirubin were significantly restored towards normalization with the treatment of CT. The biochemical observations were supplemented with histopathological examination of liver sections. Liv-52 was used as standard reference and exhibited significant hepatoprotective activity against carbon tetrachloride induced hepatotoxicity in rats. The results of this study strongly indicate that, methanolic extracts of blue and white flowered varieties of CT have potent hepatoprotective action against carbon tetrachloride induced hepatic damage in rats. Methanol extract of white flowered variety (MEWFV) effectively control SGOT, SGPT and ALP as compared to methanol extract of blue flowered variety (MEBFV). MEWFV of CT showed more significant hepatoprotective activity as compared to MEBFV of CT. This study suggests that possible mechanism of this activity may be due to free radical-scavenging and antioxidant activity, which may be due to the presence of phenolic compounds in the extracts.

To read the full article Peer-reviewed Article PDF image

Author(s): Patil Amol P Patil Vijay R

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version