alexa Abstract | Comparative study of marker of oxidative stress among normotensive, pre-hypertensive and hypertensive subjects.

Biomedical Research
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Abstract

This study was undertaken to evaluate the serum levels of antioxidant enzymes and marker of lipid peroxidation and compare oxidative stress level among normotensive, prehypertensive and hypertensive subjects. In this cross sectional study 25 normotensive,15 prehypertensive and 25 hypertensive subjects were included. The potential participants were subjected to selection protocol consisting of clinical history, physical examination and appropriate test. All subjects underwent blood pressure measurement and markers of oxidative stress were estimated in serum. Exclusion criteria were smoking, diabetes, asthma, COPD, malignancies, chronic diseases, and current use of any medication including dietary supplements Present study showed strong association of oxidative stress with high blood pressure and there was positive correlation between marker of oxidative stress and systolic and diastolic blood pressure.

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Author(s): Aquil Ahmad Mohd Mobark Hossain Usha Singhal Najmul Islam

Keywords

Essential hypertension, Oxidative Stress, Oxidative Stress markers, Catalse, Glutathione peroxidise, Superoxide dismutase, Malondialdehyde

 
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