alexa Abstract | Comparison Of Diffusion And Permeability Of Selected Drugs : Effect Of Physicochemical Properties And Permeation Enhancers

Indian Journal of Pharmaceutical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Short Article Open Access

Abstract

An attempt was made to compare and assess the permeability characteristics of selected drug molecules by varying lipophilicity and molecular weight using in vitro diffusion assembly and everted small intestinal sac model. Apparent permeability coefficient, flux, permeability coefficient and enhancement ratio of selected drug molecules through both the models were compared. The permeation data was compared with physicochemical properties including solubility parameter of drug molecules. In vitro data was found to be higher than the data obtained from everted sac model. Permeation of drugs through everted sac model was significantly enhanced by incorporation of sodium taurocholate (1%), which could be correlated with in vitro diffusion data.

To read the full article Peer-reviewed Article PDF image

Author(s): Sarasija Suresh H P Joshi

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords