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Although the value of exchange transfusion in the treatment of neonatal hyperbilirubinae-mia is recognized, the procedure has some risks and complications. Medical records of 92 newborns who under went exchange transfusion between September 2006 and August 2008 at Sher-I-Kashmir institute of medical sciences Soura Srinagar Kashmir were studied to de-termine the cause of jaundice and adverse events associated with neonatal exchange transfu-sion performed for hyperbilirubinemia. ABO incompatibility was the commonest cause for neonatal hyperbilirubinemia and was found in 25% followed by Rh. incompatibility in 21.3%. None was found to have G6PD deficiency. Complications fallowing exchange trans-fusion were found in 20.7% neonates. Thrombocytopenia was found in 6%, Hypocalcaemia in 4.3%, Bradycardia, seizures, disseminated intravascular coagulation, Cardio respiratory arrest, hypoxia, necrotizing enter colitis and apnea were found in 1% each. The over all mortality observed was 2.1%. The majorities of adverse events associated with exchange transfusion were laboratory abnormalities and were asymptomatic and treatable.
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Author(s): Abdul Wahid Bhat Churoo BA Qazi Iqbal Sheikh MA Javeed Iqbal Rubina Aziz
Hyperbilirubinemia, Exchange transfusion (ET), Neonates