alexa Abstract | Computational modeling of amperometric choline biosensor for neurochemical detection

Biomedical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access


The behavior of biosensors is based on the well-defined physical, chemical and biological reactions, which are expressed by nonlinear differential equations. The characteristics of diffusion reaction of choline biosensor are analyzed mathematically for wide range of input parameters such as initial concentration of choline and thickness of choline oxide enzyme layer. The mathematical simulations are done in MATLAB software using partial differential equation solver pdepe function. The analytical results are compared with numerically simulated results for various conditions to validate the model parameters. A numerical simulation result shows less than 2% deviation from analytical results for various substrate concentrations. For dimensionless diffusion distance x=0 and sigma=1, the dimensionless substrate and product concentrations are 0.72 and 0.18 when t=1 and changes exponentially with time.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): P Ravikumar N Jeyashanthi S Arumugam


Choline, Biosensor, Pdepe, Mathematical modeling, MATLAB, #

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version