alexa Abstract | Coordination chemistry and biological activity of different types of antibiotics

Journal of Chemical and Pharmaceutical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Original Articles Open Access


Metal complexes of antibiotics have powerful antimicrobial activities and are used in medicinal field such as silver bandages for treatment of burns, zinc antiseptic creams, bismuth drugs for the treatment of ulcers and also as anti- HIV drugs. The chelating properties of metals were used to prepare metal complexes of all the classes of antibiotics as metalloantibiotics. Although most antibiotics do not need metal ions for their biological activities but, there are some of antibiotics that require metal ions for maintaining proper structure and/or function of these antibiotics, such as bleomycin, streptonigrin and bacitracin. Metalloantibiotics can interact with several different kinds of biomolecules, including DNA, RNA, proteins, receptors, and lipids, rendering their unique and specific bioactivities. In addition to antimicrobial activity of metalloantibiotics, also show antiviral and antineoplastic activities which provide a various function of the term metalloantibiotics. Bismuth-fluoroquinolone complexes have developed as drugs against H. pylori related ailments. Antibiotics metal complexes and the mixed antibiotics metal complexes were found more effective as chemotherapy agents than their parent antibiotics.

To read the full article Peer-reviewed Article PDF image

Author(s): Mamdouh S Masouda Ala E Ali and Nessma M Nasr



Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version