alexa Abstract | Cortical Evoked Response Audiometry Thresholds and Neuroleptic, Sedative, Hypnotic Drugs

The International Tinnitus Journal
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access

Abstract

Cortical evoked response audiometry is adequate for approximating hearing threshold levels with frequency specificity when the psychoacoustic responses lack reliability and reproducibility (compensation claim). It is well-known that control of wakefulness is essential for the reliability of slow vertex responses (SVR). Therefore, sedative, hypnotic, and neuroleptic drugs are supposed to have possible adverse effects on the detection' of SVR. In contrast, brains tern evoked responses (BER) have proved not to be significantly affected by therapeutic doses of these compounds. The purpose of our study was to assess the reliability of SVR-threshold definition in subjects taking neuroleptic, sedative, and hypnotic drugs. Fifteen subjects examined for occupational hearing loss at the Fund for Occupational Diseases in Brussels and regularly taking one or several of these drugs were compared with 27 comparable controls. In each subject the auditory thresholds were defined with both techniques: SVR (1, 2, and 3 kHz) and BER (clicks). A highly significant difference is observed between the two groups: In the group receiving drugs, the SVR threshold for 3 kHz is 12.1 dB (average) higher than the BER threshold, whereas in the group without drugs, the SVR threshold for 3 kHz is 7.77 dB (average) lower than the BER threshold. In the drug group, large interindividual differences are observed. It may be concluded that the use of neuroieptics, sedatives, and hypnotics renders the auditory threshold definition with SVR completely unreliable. In using SVR for medicolegal threshold definition, controlling the 3-kHz threshold with BER always is necessary.

To read the full article Peer-reviewed Article PDF image

Author(s): Philippe H Dejonckere Jean Lebacq and Christiane Coryn

Keywords

cortical response audiometry, evoked potentials, forensic medicine, hypnotics, legal medicine, neuroleptics, sedatives, slow vertex responses

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords