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Research Paper Open Access
The cytotoxic principles of Ixora javanica was separated from 50 percent ethanol extract by ethyl acetate and purified by paper chromatography using butanol acetic acid water (6:1:2). The active fraction was cytotoxic on DLA EAC and S-180 cells at a concentration of 30;90 and 20 gms respectively. The mechanism of action is probably at the DNA level.