alexa Abstract | Cytotoxic action of ixora javanica leaves.

Indian Journal of Pharmaceutical Sciences
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The cytotoxic principles of Ixora javanica was separated from 50 percent ethanol extract by ethyl acetate and purified by paper chromatography using butanol acetic acid water (6:1:2). The active fraction was cytotoxic on DLA EAC and S-180 cells at a concentration of 30;90 and 20 gms respectively. The mechanism of action is probably at the DNA level.

Author(s): SC Nair KR Panikkar

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