alexa Abstract | Design, synthesis and biological evaluation of dihydroisoxazole of indole derivatives as anti-microbial agents

Journal of Chemical and Pharmaceutical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Original Articles Open Access


In the present study, a new series of Oxazoline derivatives [5a-5l] were prepared from the N-cyclopentyl indolyl chalcones [4a-4l] with hydroxylamine hydrochloride in presence of base gives 65-78% yield after column purification. The purity of the compounds was checked by TLC in ethylacetate: hexane (3:7). The structures of all the compounds were established by 1H - NMR, IR, LCMS. The synthesized compounds [5a-5l] were evaluated for their anti-microbial activity. Out of 12 compounds reported here, many of them displayed decent anti-bacterial and anti-fungal profiles. We report herewith most prominent molecules 5c, 5d, 5l have been identified as the lead with the most prominent results.

To read the full article Peer-reviewed Article PDF image

Author(s): Babasaheb Zine Sunil Jadhav and Mazahar Farooqui


Chalcones, Anti-microbial activity, Indole, hydroxylamine hydrochloride., indole,anti-microbial agents

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version