alexa Abstract | Detection of Aneuploidy in Neural Stem Cells of the Developing and Adult Human Brain

Electronic Journal of Biology
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)


Neural stem cells (NSCs) are found to be present in the developing and adult human brain. The genuine interest to the properties of NSCs in the light of recent advances in neurosciences, developmental biology and molecular medicine has forced to reconsider genetic features of the developing and adult human brain, which are, as yet, incompletely known. A series of articles has reported that genomic variations manifested as aneuploidy (losses/gains of whole chromosomes in a cell) hallmarks the development of the human brain and that aneuploid cells populate the adult human brain. This has led to the creation of a new biomedical direction termed molecular neurocytogenetics. Although the studies in the field use previous developments of molecular cytogenetics, there is apparent interest in considering both advantages and disadvantages of the techniques in context of studying NSCs in the developing and adult human brain. The outcomes of such evaluation will be probably found valuable for designing future NSC studies. Here, molecular cytogenetic approaches allowing single-cell monitoring of chromosome complement variations are considered in context of different applications in NSC research. The data presented simplifies the choice between molecular cytogenetic techniques for obtaining better results during forthcoming NSC studies.

To read the full article Peer-reviewed Article PDF image

Author(s): Ivan Y Iourov Svetlana G Vorsanova Yuri B Yurov


aneuploidy, human brain, fluorescence in situ hybridization (FISH), molecular cytogenetics, neural stem cells (NSCs).

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version