alexa Abstract | Development and validation of a reverse phase HPLC method for the simultaneous estimation of Metoprolol and Telmisartan in tablet dosage form

Der Pharmacia Sinica
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access


Present work describes a simple, accurate, precise and reproducible reverse phase High Performance Liquid Chromatographic method for simultaneous estimation of Metoprolol and Telmisartan in tablet dosage form on RP C-18 Column ( Hypersil Gold, 25cm x 4.6mm, 5μm) using Acetonitrile and buffer (0.05M KH2PO4, pH 3.0±0.02, 35:65 v/v) as mobile phase at a flow rate of 1.0 ml/min and the detection wavelength was 225nm. The retention time for Metoprolol and Telmisartan was found to be 3.71 and 10.02 min. respectively. Detection response for both Metoprolol and Telmisartan were found to be linear low in concentration range of 29.88-69.72mcg/ml and 24.12-56.27mcg/ml respectively in the linearity study, regression equation and coefficient of correlation for Metoprolol and Telmisartan were found to be (y = 33409x + 5518, r2 =0.9999) and (y = 111545x – 5850.4, r2 = 0.9999). Proposed method was validated for accuracy, precision, linearity, range, ruggedness & robustness.

To read the full article Peer-reviewed Article PDF image

Author(s): Joshi Pryanka and Kumar Mukesh


Metoprolol, Telmisartan, RP- HPLC, U.V.

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us