alexa Abstract | Development and Validation of a Spectrophotometric method for estimation of Rasagiline Mesylate in bulk and tablet dosage Form

International Journal of Drug Development and Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)


Rasagiline mesylate is a new molecule which acts as irreversible monoamine oxidase inhibitor used for the treatment of idiopathic parkinson’s disease. The aim of present work was to develop a simple, accurate, reproducible and cost effective spectrophotomeric method for determination of Rasagiline mesylate in a pharmaceutical dosage form using phosphate buffer pH 6.8 as a solvent. The drug in solution form showed absorption maxima at 265 nm and obeys Beer’s Lambert’s law in concentration range 100-300 μg/ml. The regression equation was y = 0.003x + 0.0056 and correlation coefficient of (R²) 0.9995. The limit of detection and limit of quantification was found to be 2.915 μg/ml and 8.833 μg/ml. Percent relative standard deviation values for the intra-day and inter-day precision were found to be 0.4308 and 0.6160 respectively. Mean % recovery was 100.45%. The proposed method was successfully applied for determination of Rasagiline mesylate in a tablet dosage form without any interference from common excipients.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Patel Pinal R Mulgund Sugandha V


Rasagiline Mesylate, Validation, UV Spectrophotometric

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version