alexa Abstract | Development and Validation of Analytical method for Lopinavir and Ritonavir by HPLC

International Journal of Drug Development and Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Abstract

This paper describes the development and validation of the HPLC method (254nm) for the quantitation of lopinavir and ritonavir in pure form and pharmaceutical formulations. The method showed to be linear (r2 > 0.999), precise (R.S.D. < 0.21%), accurate (recovery of 100.11% for lopinavir and 99.96% for ritonavir), specific and robust. Three batches of lopinavir and ritonavir tablets were assayed by the validated method. The lopinavir contents in the tablets varied from 99.87 to 100.52%, while ritonavir contents showed 99.61 to 100.57%.

| Peer-reviewed Full Article image

Author(s): R Arun A Anton Smith

Keywords

Lopinavir, Ritonavir, Antiretrovirals, HPLC-UV

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us