alexa Abstract | Development of analytical method for efavirenz by UV spectrophotometry using sodium hydroxide as solvent

Der Chemica Sinica
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access

Abstract

The main aim of the present study is to develop a simple, sensitive, specific, spectrophotometric method developed for the detection of Efavirenz in bulk drug and pharmaceutical formulation. The optimum condition for the analysis of the drug was established. The wavelength (λmax) of the Efavirenz was found to be 267nm. The proposed method can be performed by using UV-Visible spectrophotometry using 0.5N NaOH as solvent. The regression coefficient of the linearity study was found to be 0.9918, and the slope of the linear is y=0.0738x. This method shows the linearity of 2 to 12μg/ml. Limit of detection was found to be 0.454μg/ml and the Limit of quantification was determined as the lowest concentration was found to be 1.499μg/ml. The proposed method will be suitable for the analysis of Efavirenz in bulk and pharmaceutical formulation

To read the full article Peer-reviewed Article PDF image

Author(s): Anton Smith A Maruthi G Velmurugan A and Parimalakrishnan S

Keywords

Efavirenz, Spectrophotometry, Estimation, chemistry

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us