alexa Abstract | Development of new Analytical Methods and their Validation for the Determination of Tizanidine Hydrochloride in Bulk and Marketed Formulations

Asian Journal of Biomedical and Pharmaceutical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Abstract

Tizanidine Hydrochloride in presence of acidic medium reacts with excess amount of potassium bromide-bromate and unreacted potassium bromidebromate react with malachite green to produce green colour.The final stock solution was made to produce 100μg/ml with distilled water. The λmaxwas found to be 617nm for assay. The linearity was found in concentration range of 10-30μg/ml. The correlation coefficient was found 0.999. The regression equation was found as Y=0.009x + 0.002. The method was validated according to ICH Guidelines.

To read the full article Peer-reviewed Article PDF image

Author(s): Sumit Saparia Padmavathi P Prabhu Dr EVS Subrahmanyam Jignesh Kaneria Sagar Bechara Dr ARShabaraya

Keywords

Tizanidine Hydrochloride, malachite green, potassium bromidebromate, HCl.

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords