alexa Abstract | Diagnostic and prognostic role of Procalcitonin in sepsis in a tertiary care hospital.

Biomedical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)


Background: Bacterial sepsis is one of the common causes of morbidity and mortality in patients admitted to any tertiary care hospital. Early diagnosis of bacterial sepsis is a challenge to the clinician and the laboratory. Blood culture is the gold standard for the diagnosis of bacterial sepsis. Isolating the bacteria and determining its antibiotic susceptibility takes a minimum of 48 hours. There is a constant search for biochemical markers which might rapidly indicate bacterial sepsis. Aim: The aim of the study was to evaluate the diagnostic and prognostic role of procalcitonin in bacterial sepsis. Subject and methods: Procalcitonin (PCT) levels were determined in 136 patients admitted to the hospital with symptoms of sepsis. PCT was measured in serum samples obtained from the patients at the same time when blood was drawn for culture. Results: Out of the 136 patients clinically diagnosed with sepsis, 14 patients had a positive blood culture (10.3%). Procalcitonin levels of >0.5 ng/ml was considered as positive. Out of the 14 patients with a positive blood culture, 12 had PCT levels greater than 0.5 ng/ml. ROC analysis revealed maximum sensitivity of 64% and a specificity of 65% with a PCT value of 3.25 ng/ml. The mean PCT values in survivors were lower when compared to PCT values in non survivors. Conclusion: Markers for rapid diagnosis of sepsis is required to institute rapid and appropriate management. Procalcitonin level is one such promising target marker for early diagnosis of sepsis.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Sunil Kumar Nanda Asha Dinakaran Sandhya Bhat K Ravichandran Reba Kanungo



Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version