alexa Abstract | Diagnostic Yield of Sural Nerve Biopsy: Study from a Tertiary Care Referral Centre in India

Journal of Neurology and Neuroscience
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access


Background: Peripheral neuropathies are a heterogeneous group of disorders with varying etiologies. A systematic approach is required for patient evaluation for cost effective diagnosis. Aims: Present study conducted at a tertiary care referral centre aimed to evaluate the clinical profile and usefulness of sural nerve biopsy.

Material and method: The study was conducted on 75 patients attending the neurology outpatient department/those admitted in the wards. All patients were subjected to a detailed clinical, neurological and necessary biochemical investigations. Those patients with an inconclusive result were subjected to a sural nerve biopsy with the results being interpreted as diagnostic, contributory or noncontributory.

Results: Out of the 75 patients enrolled 36 underwent nerve biopsy. Amongst those 18 turned out to have Hansen’s disease, 8 vasculiis, 2 CIDP, 1 diabetes and 7 patients remained undiagnosed. Overall in 15 cases the biopsy was diagnostic, in 14 cases it was contributory, while in 7 cases it was noncontributory. Nerve biopsy proved more beneficial in patients with a multiple mononeuropathy pattern (p<0.003). Overall in about 80% of patients nerve biopsy proved to be worthwhile

Conclusion: Nerve biopsy has a good diagnostic yield if done in properly selected cases. This is especially so for the asymmetrical neuropathies particularly infectious causes like leprosy and vasculitis.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): SP Patidar Deepika Joshi Mishra VN Chaurasia RN Ansari AZ and Niraj Kumar


Nerve biopsy, Peripheral neuropathy, Sural nerve, Central nervous system,Neuroscience,Clinical Neuroanotomy

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us