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Review Article Open Access
Till date, the emphasis in dissolution has been only limited to calculating percent drug release as specified in different pharmacopoeias. But, now dissolution testing has become one of the most important tests in quality control of dosage forms. These in vitro dissolution studies can also be used to ensure acceptable in vivo performance. Therefore, it is desirable to develop dissolution testing that can assess the ability of a dosage form to release the drug completely and simultaneously indicate the drug's performance in vivo. The present review gives an insight about the various factors which must be taken into consideration to get perfect in vitro in vivo correlation.
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Author(s): Shipra Ahuja Alka Ahuja Sanjula Baboota J Ali