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Original Articles Open Access
In Pharmaceutical field, the search for compound that have suitable properties to be used in nowadays a big challenge, paracetamol, one of the most widely used drug is taken and the effect of dopant EDTA on the growth process, crystalline properties of paracetamol are investigated. The grown crystal was transparent, obtained within a period of few days. The grown crystal was subjected to various studies, such as X-Ray Diffraction(XRD), Fourier Transform Infrared (FTIR) and Ultraviolet-Visible (UV-Vis) absorbance, Thermogravimetric analysis and Differential thermal analysis (TGA/DTA). The functional groups of the crystals have been confirmed by FTIR analysis. The lattice parameters of the grown crystal were determined by single crystal XRD. A UV-Vis spectrum was recorded to find the suitability of the crystal for optical applications and band gap energy is determined. The thermal stability of doped crystal was checked using the TGA/DTA analysis. The surface morphology of the crystal was analysed by SEM and EDAX analysis was also carried out.
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Author(s): B Kavitha G Madhurambal and S Nelson Amirtharaj
Crystal growth, FTIR, Thermogravimetric analysis, UV-Vis, XRD, paracetamol drug