alexa Abstract | Effect of ZnO NPs on tumor marker hormones in male rats.

Biomedical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)


ZnO nanoparticles (NPs) are engineered nanoparticles used in many commercial products inclusive of cosmetics, paints, textiles, and sanitary products. ZnO NPs are potent in protecting the skin against UV radiation so, they are used as ingredients in sunscreen and moisturizing creams/lotions and hence the study of their toxicity is essential. On the one hand, nanoparticles, due to their small size occupy a significant place in cutting-edge applications in modern industry, while on the other hand; the small size of NPs may lead to their accumulation in the body leading to health hazards in human beings .The effect of ZnO NPs in different concentrations on Prostate Specific Antigen (PSA), 1- α- fetoprotein (AFP), and carcinoembryonic antigen (CEA) of male Wistar rats assigned in four groups, each consisting of 8 rat, was investigated. ZnO NPs was gavage-fed to groups 1, 2, and 3 with concentrations of 100, 200, and 400 mg/kg respectively for 10 days. A separate group of animals was assigned as the control group. Subsequent to the phase, tumor marker hormones AFP, CEA, and PSA concentrations were estimated. Results showed that ZnO NPs is toxic in the animal model. Thus, it is proposed that the NPs should be applied taking into consideration the health hazard that it might cause and a continuous monitoring of individuals’ health is essential.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Habibollah Nazem and Zahra Arefian


ZnO, tumor marker, AFP, CEA, PSA.

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us