alexa Abstract | Efficient click synthesis of substituted para acetamido benzene sulfonyl-1, 2, 3 –triazoles using PABSA and various terminal alkynes through cycloaddition

Journal of Chemical and Pharmaceutical Research
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A two component reaction is used to prepare a series of disubstituted para-acetamidobenzenesulfonyl-1, 2, 3– triazoles from para acetamido benzene sulfonyl azides (PABSA) and terminal alkynes, also it reacts with opropargylated terminal alkynes. This procedure eliminates the need to handle organic azides, as they are generated in situ, making this already powerful click process even more eco-friendly and safe through 1,3- dipolarcycloaddiation

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Author(s): Jagadeesh Kumar Ega and Ravinder Vadde


Triazole, PABSA, Terminal alkyne’s, Cycloaddition, benzene

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