alexa Abstract | Enhanced healing process of fracture by treatment of Kaempferol.

Biomedical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)


Recently, plant-derived phytoestrogens have been shown to possess promising results for bone preservation and bone augmentation. Kaempferol, one of flavanols, is known to possess osteogenic effects and ability to stimulate bone formation. This study was designed to investigate the effect of Kaempferol on the process of bone healing in standardized mouse tibia fracture model. Oral administration of Kaempferol (0.2, 0.5 and 5 mg/kg body weight) to mice with fractured tibiae demonstrated an increase in callus formation and new bone formation as evidenced by the measurement of callus diameter and H&E staining, respectively at 21 days post-fracture. In addition, radiographic examination carried out at early stages of fracture healing process (11 days and 14 days post-fracture) revealed prior appearances of denser and bigger calluses in Kaempferol (0.5 mg/kg) treated group than that from control. Taken together, it can be concluded that Kaempferol potentiates fracture healing by increasing callus formation and initiating bone remodeling process.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Lich Thi Nguyen Otgonbayar Maidar Ashish Ranjan Sharma Garima Sharma Heung Cheol Kim Seonghun Park SangSoo Lee JuSuk Nam



Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version