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Background: Eosinophilic granuloma is the benign form of Langerhans cell histiocytosis, a rare proliferative disorder. Skull osteolytic lesions are quite frequently encountered.
Case report: We report the case of a 16 year old boy who was admitted to our Department with a painful swelling left frontal mass. A diagnosis of eosinophilic granuloma was presumed on the basis of the neuroradiological findings. Surgical removal of the lesion was achieved and the bone defect reconstructed by autologous fibrin glue and a titanium mesh. Histopathology confirmed the diagnosis.
Conclusion: Although uncommon, eosinophilic granuloma should be considered in the differential diagnosis in case of an osteolytic calvarial lesion.
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Author(s): Alessia Imperato Domenico Gerardo Iacopino Francesca Graziano Carlo Gul Antonella GiugnoLuigi Basile Rosario Maugeri
Eosinophilic granuloma, Langerhans cell, Calvarial bone, pediatric