alexa Abstract | Esophageal Candidiasis in an Immunocompetent Girl with Chronic Anaemia

Journal of Gastroenterology and Digestive Diseases
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Case Report Open Access


Infection is an uncommon cause of esophagitis among the paediatric population. The main risk factor is immunodeficiency. In children immunocompromised due HIV infection, certain endocrine diseases, and corticosteroid or immunosuppressive therapy, Candida albicans is the most common etiologic agent. The prevalence of Candida esophagitis has increased because of an improvement in survival and management of immunological diseases. Even though it is not frequent in immunocompetent children, there have been reported cases related with risk factors (Chocarro, 2000) such as antibiotic intake (which allow bacterial overgrowth and fungal colonization), proton pump inhibitors (which produce hypochlorhydria allowing oral bacteria to colonize gastric mucosa, and to increase the risk of infectious esophagitis), esophageal obstruction (aperistalsis and stasis helps the fungal overgrowth) and systemic or inhalated corticotherapy (that suppresses lymphocyte and granulocyte function) (Simon, 1997). Candida esophagitis has also been reported in healthy patients, with no evidence of causal mechanism (Alemán, 1996). The most common symptomatology consists in odynophagia, dysphagia and retrosternal chest pain, but epigastralgia, vomiting and gastrointestinal bleeding can also occur. Chronic or acute anaemia could be the sole sign of an asymptomatic presentation (Ortuño Cortés, 1997., Weerasuriya, 2006). The absence of oral candidiasis does not exclude the diagnosis of Candida esophagitis (Mathieson, 1983). The pathophysiology of the infection is complicated. It includes a large number of factors, such as fungal virulence, mucosal integrity and host susceptibility. Esophagoscopy is the most specific and sensitive method of diagnosis. Characteristic endoscopic findings are confluent or isolated white plaques adhered to the mucosa with edema, erythema and friability, with or without ulcers covered by exudate. The diagnostic confirmation is performed by demonstrating the presence of pseudohyfae or by obtaining evidence of tissue invasion on mucosal biopsy (Ahuja, 2016). Fungal culture does not allow differentiation of colonization from infection (Mathieson, 1983). The treatment of choice is fluconazole, but there are new therapeutic options (Ahuja, 2016).

To read the full article Peer-reviewed Article PDF image

Author(s): Barros Garca Patricia Izquierdo Martn Ana De Nicols Jimnez Jorge Manuel Lpez Lafuente Amparo Mateos Rodrguez Jos Mara Gonzlez Nez M ngeles LpezRodrguez M Jos


Esophageal candidiasis, Oesophageal cancer, Pancreatic cancer, Perianal diseases, Polyps in the bowel

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

1-702-714-7001Extn: 9037

Business & Management Journals


1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version