alexa Abstract | Evaluation of anti-Candida albicans activity of essential oils of six medicinal plants: Synergy concept

Journal of Chemical and Pharmaceutical Research
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Abstract

T his study is to evaluate the anti - Candida alb icans activity of essential oils of six medicinal plants and to seek some synergistic association s between essential oils or essential oils and a reference antifungal . Essential oils are extracted from six medicinal plants; their antifungal power is studie d alone or in combination. The culture medium is Sabouraud - chloramphenicol (0.5 g / L), the minimum inhibitory concentrations (MIC) are determined by the macrodilution method. The dilution solution is 0.2% agar . Essential oils studied have a strong anti - Candida albicans power; the associations show a synergistic effect between these oils in most cases. Combination of essential oils with amphotericin B reduces the MIC of the antifungal and therefore reflects a synergistic association. This study shows that essential oils studied exert a synergistic effect between them and in combination with amphotericin B, which can reduce the doses of this product while increasing anti - Candida albicans activity

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Author(s): Hakim El Alama AchaEl Aissami Amal Ait Haj Saidand FatimaEzzahra El AlaouiFaris

Keywords

Candida albicans, essential oils, amphotericin B, synergy, anti-Candida albicans, Synergy concept

 
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