alexa Abstract | Evaluation of antitumour activity and antioxidant status in Dioscorea hispida, Dennst. leaves on Ehrlich Ascites Carcinoma in Swiss Albino Mice

International Journal of Drug Development and Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Abstract

Cancer’ is a malignant disease that is characterized by rapid and uncontrolled formation of abnormal cells which may mass together to form a growth or tumour, or proliferate throughout the body. Next to heart disease, cancer is a killer of mankind. The present study aims at a preliminary phytochemical analysis and anticancer evaluation of Dioscorea hispida, Dennst. against Ehrlich Ascites Carcinoma in animal model. The results indicate that ethanolic extract of Dioscorea hispida leaves (DhLE) possess significant anticancer activity at the dose varying from 100mg/kg to 200mg/kg body weight. It has increased the survival of animals with ascites tumour, decreased the body weight induced by the tumour burden, reduced packed cell volume and viable tissue cell count and also reduce elevated level of lipid peroxidation due to higher content of Phenolic compounds. Thus DhLE may have therapeutic application against cancer.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Punith kumar T G Panduranga Murthy G Suresh A Suresh VSenthil kumar N and Raviashankar H G

Keywords

Dioscorea hispida, Dennst. Lipid peroxidation, Ehrlich Ascites Carcinoma (EAC), Anticancer

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords