alexa Abstract | Evaluation of diuretic propertiesfrom Elaeis guineensis Jacq. (Arecaceae) leaves aqueous extractin Wistar rat

Journal of Chemical and Pharmaceutical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Original Articles Open Access


The main aim of the present investigation was to appreciate the diuretic and natridiureticactivities and the toxicity from Elaeis guineensis leaves aqueous extract (EGLAE). After orally administration of the aqueous extract at doses of 67.5 mg/kg, 135 mg/kg and 202.50 mg/kg (body weight) to Wistar rat, the volume of urine excreted and the quantity of ions (Na+, K+) are respectively determined in stepped up test-tube and by ionic spectrophotometrically measuring. The results show that the urine of Wistar rathas a pH between 6.1 and 8.6 with an average of 7.35 ± 1.25. Diuresis basic after six hours is 7.8 mL. A significant diuretic activities (157.16%, 169.25%) areobserved in Wistar rattreated respectively with 135 mg/kg of EGLAE and furosemide (as reference drug, 20 mg/kg) and a modest diuretic activity (146.32%) with a dose of 202.50 mg/kg of EGLAE. Itnatridiuretic activity was 2.34 at same dose of 135 mg/kg against 2.52 for furosemide (20 mg/kg) and 0.75 for distilled water. The dose of 135mg/kg is the best in terms of diuretic and natridiureticactivities.IC50 of larval toxicity of aqueous extract on Artemia salina has evaluated to be1.710 mg/mL.

To read the full article Peer-reviewed Article PDF image

Author(s): Fidle MAssogba Chouaibou Aderomou Wilfrid Agbodjogbe Mansourou Moudachirou and Joachim D Gbenou


Elaeis guineensis, diurétic activity, Wistar rat, toxicity

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us