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Original Articles Open Access
The microbeads were prepared by an industrially feasible micro orifice ionotropic-getation method using glutinous rice starch from Assam Bora rice, and sodium alginate backbone with different crosslinking agents. The microbeads fabricated through several preformulation trials were evaluated in reference to drug release, drug excipient compatibility and mucoadhesive potential. The effect of various formulation and processing parameters was studied by scanning electron photomicrographs taken before and after dissolution. Photomicrographs provides the information about the surface texture, size, mechanistic properties, suitability of drying condition and mechanism of drug release from the prepared micro devices.
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Author(s): Nikhil K Sachan S K Ghosh and A Bhattacharya
Microbeads, scanning electron microscopy, drug delivery, glutinous starch.