alexa Abstract | Evaluation of protective effects of water extract of Spirulina platensis (blue green algae) on cisplatin-induced lipid peroxidation

Indian Journal of Pharmaceutical Sciences
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Research Paper Open Access


Attempt has been made to evaluate free radical scavenging activity of water extract of Spirulina platensis on cisplatin-induced lipid peroxidation using some common laboratory markers. In this present study goat liver has been used as lipid source. This in vitro evaluation was done by measuring the malondialdehyde, 4-hydroxy-2-nonenal, reduced glutathione and nitric oxide content of tissue homogenates. The results suggest that cisplatin could induce lipid peroxidation to a significant extent and it was also found that water extract of the algae has the ability to suppress the cisplatin-induced toxicity.

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Author(s): S Ray K Roy Chandana Sengupta

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