alexa Abstract | Evaluation of the analgesic activity of Cissus aralioides leaves in rat

Journal of Chemical and Pharmaceutical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Original Articles Open Access

Abstract

The study evaluated the analgesic effects of methanolic extract of Cissus aralioides leaves in rats. The analgesic effects of C. aralioides was evaluated using acetic acid induced writhing reflex and tail flick models in rats. The administration of the extract at the doses of 150, 300 and 600 mg/kg body weight to the rats resulted in a significant (P < 0.05) decrease in the number of writhing reflexes in rats in a dose dependent manner when compared to tween- 20 solution treated group (negative control). In the tail flick model, Pre-treatment of the rats with Aspirin (100 mg/kg), extract (300 and 600 mg/kg) produced 59.25%, 21.71% and 22.59% increase in pain reaction time (PRT) respectively, when compared to the negative control group. The result of the study suggests that Cissus aralioides possesses analgesic properties and provides the pharmacological basis for its use in ethnomedicine for this purpose.

To read the full article Peer-reviewed Article PDF image

Author(s): Maxwell I Ezeja Samuel O Onoja Celestine O Ukwueze and Gideon K Madubuike

Keywords

Analgesia, Cissus aralioides, writhing reflex, acetic acid, Aspirin, tail flick

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords