alexa Abstract | EVALUATION OF THE IMMUNOMODULATORY ACTIVITY OF THE METHANOLIC AND ETHANOLIC EXTRACT OF LEAVES OF AEGLE MARMELOS IN RATS

International Journal of Drug Development and Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Abstract

Aegle marmelos, belongs to family Rutaceae is generally known as bael fruit. They were evaluated for potential immunomodulatory activity using the in vitro Polymorphonuclear leukocyte function test. Both Methanolic and Ethanolic extract of Aegle marmelos leaves were evaluated for their immunomodulatory activity. In in vivo studies, using rats as the animal model. The extract was tested for hypersensitivity and hemagglutination reactions, using shed red blood cells (SRBC) antigen. The methanol extract exhibited a significant increase in the percentage phagocytosis versus the control. It was noted to exhibit a dose related increase in the hypersensitivity reaction, to the SRBC antigen, at concentration of 100 & 200 mg/kg. It also resulted in a significant increase in the antibody titer value, to SRBC, at doses of 100 and 200 ml/kg in animal studies. The Methanolic extract was found to stimulate cell mediated and antibody mediated immune responses in rats.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Ankur Choubey Aadarsh Choubey Ashish Mishra Shilpi Mishra U KPatil

Keywords

Aegle Marmelos, Hypersensitivity, Hemagglutination, Immunostimulant

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords