alexa Abstract | Evaluation of the Performance of Melia Azedarach for Skin Wound Healing in Donkeys: Clinical and Histopathological Study

American Journal of Phytomedicine and Clinical Therapeutics
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access

Abstract

Objectives: To determine clinical and histopathological efficacy of Melia azedarach in healing of surgical skin wound.
Methods: Incisions of 10 -12 cm length created bilaterally in the thigh, flank and neck in (6) donkeys, 4 – 5 years old, 150 kg body weight. Melia azedarach ointment (10%) applied on wounds daily for 14 days. Biopsies from wounds for histopathology taken on day 5, 10 and 15 respectively.
Results: Histopathological sections at 5th day for non-infected wounds treated with melia azedarach revealed PMNs infiltration and fibrin exudates. Acute inflammatory cell infiltration, necrosis of the epidermis as well as sloughing were detected in infected wounds treated with Melia azedarach. in10th day, in treating non infected wounds a fibrous connective tissue proliferation, formation of new blood vessels and collagen bundle formation were noticed.
Infected wounds treated with melia azedarach, inflammatory reaction extend from epidermal, dermal to the muscular layer noticed. In nontreated non-infected wounds, replacement with fibrous connective tissue noticed. At 15th day, in treating non infected wounds, regeneration of sweat and sebaceous glands, formation of smooth muscle fibers, mature connective tissue replacement, many newly formed blood vessels noticed. In treated infected wounds, inflammatory cell infiltration in subcutaneous tissue, fibrous connective tissue proliferation noticed. In non-treated non-infected wounds, slight inflammatory reaction, noticed.The wounds clinically healed on day 15, and it was better in both wounds in thigh regions, followed by that on flank regions.
Conclusion: Melia azedarach has an Ã¯Â»Â¿ slight  anti inflammatory reaction and antibacterial activity and used effectively in treatment of infected wounds, which completely heal in 15 days.

To read the full article Peer-reviewed Article PDF image

Author(s): AlKhafaji Nazar Falah H Khalaf Ahmed H ALZuhairi and Ali Ibrahim Ali AlEzzy

Keywords

Melia azedarach, Wound, Histopathology., Phytomedicine, Therapeutics

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

chem[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords