alexa Abstract | Evaluation the effects of cefteriaxone injection on some biochemical factors in layer chickens

European Journal of Experimental Biology
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Research Article Open Access


Cefteriaxone is a third generation injectable cephalosporin agent, which retains the gram positive activity of the first and second generation agents, but in comparison, have much expanded Gram negative activity. The aim of current study was to investigate the effects of Cefteriaxone injection on some biochemical factors in layer chickens during production period. In this study, 50 Hy-line W-36 layers were selected randomly and divided to five replications. During study, 50 mg/Kg Cefteriaxone was injected on days 0, 1, 5, 14 and 21. This study was performed in 28 days period and biochemical parameters include glucose, cholesterol, triglyceride, urea, uric acid, calcium, phosphor, ALP, CPK, total protein, albumin were evaluated on day zero before any cefteriaxone administration and also on days 1, 5, 14, 21 and 28 after cefteriaxone injections. Our results indicated that the glucose, Uric acid, total protein and albumin were reduced at the end of the study, and triglyceride, cholesterol, urea, calcium, phosphorus, ALP, and CPK were increased at the end study in comparison to before cefteriaxone injection. Our research results indicated that the cefteriaxone injection had affects layers biochemical indices and during production period it should be used with caution.

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Author(s): Vahid Khodabandehloo Mehdi moeil Asrami Fardin Bodaghi Seyede Soraya Mahmudi and Mohammad Reza Marsouli Oshtolagh


Layers, Cefteriaxone, Biochemical factors, antibiotic

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