alexa Abstract | Fabrication and evaluation of asymmetric membrane osmotic pump

Indian Journal of Pharmaceutical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Paper Open Access

Abstract

Asymmetric membrane-controlled porosity osmotic pumps of cellulose acetate with different pore forming agents such as glycerol, polyethylene glycol and dibutyl phthalate, were fabricated and studied for osmotic release behavior from the system. The effects of various pore-forming agents on the physical characteristics of the polymer film like tensile strength, weight variation, wall thickness, surface area, porosity and void volume were studied as a function of pore forming agent. The asymmetric membrane capsules were fabricated by dip-coating process using stainless steel mold pins of the shape of capsule body and cap and were evaluated for in situ formation of delivery pores. The effect of pore forming agents on the porosity of asymmetric membrane was characterized by scanning electron microscopy, and also by void volume determination of each membrane. Dye-test revealed that the fabricated systems followed osmotic release. Scanning electron microscopy revealed that the porosity depends upon the concentration and type of pore forming agent used. However no significant effect on the thickness and weight variation of asymmetric membrane capsule were observed, but the tensile strength of the film varied with the concentration and type of pore forming agent used. Film with polyethylene glycol-400 as pore forming agent exhibited good tensile strength.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): CS Chauhan MS Ranawat PK Choudhury

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords