alexa Abstract | Formulation And Evaluation Of Chlorpromazine Hydrochloride Loaded Self-Crosslinked Gelatin Microcapsules

Indian Journal of Pharmaceutical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Paper Open Access


Self-crosslinked microcapsules of chlorpromazine hydrochloride were prepared by coacervation phase separation technique followed by extensive dehydration at elevated temperature and pressure with gelatin. Self-crosslinked microcapsules showed about 99% of drug release within 12h, followed a first order kinetics. The in vivo studies revealed the maintenance of long duration of therapeutic effective plasma concentration without reaching the toxic level. The minimum catatonic scores in albino rats indicate that the microcapsules might even have reduced the drug-induced extrapyramidal syndrome.

To read the full article Peer-reviewed Article PDF image

Author(s): M K Samanta S Tamilvanan K Babu B Suresh

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us