alexa Abstract | Formulation Development & Evaluation of caffeine tablets (200mg) by Direct Compression

International Journal of Drug Development and Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Abstract

Direct compression is a simplest, time saving and economical way of tablets’ manufacturing. It is just a mixing and compression of dry blend of powder. The aim of study is to prepare caffeine tablets (200 mg) by direct compression. Three formulations F1, F2 and F3were prepared, containing different combinations of Avicel and DiTab, keeping the amount of drug and magnesium stearate constant. Micromeritic properties of blend and powders were determined, including carr’s index, hausner ratio, angle of repose and particle distribution analysis. Different compendial and non- compendial tests were performed to assess the quality of directly compressible tablets. F2was an optimized product as it is superior in terms of better weight variation, hardness, percent release (99.02%) and assay (100.02%).On the basis of results it is concluded that the caffeine tablets could be satisfactorily produced by direct compression.

To read the full article Peer-reviewed Article PDF image

Author(s): Kamran AlamHuma ShareefRabia Bushra

Keywords

Caffeine, Tablets, Direct Compression, Stability testing, Formulation Development

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords