alexa Abstract | Four antibacterial monoterpenoid derivatives from the herba of Senecio Cannabifolius less

Indian Journal of Pharmaceutical Sciences
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Research Paper Open Access


Fractionation of a butanol extract of Senecio cannabifolius Less. led to the isolation of two novel monoterpenoid derivatives, named cannabiside D and cannabiside E, whose structures were determined by spectroscopic analyses as 1-(2-hydroxy-2,6,6-trimethyl-4-β-D- glucosyloxy-cyclohexylidene)-butane-2, 3-dione, 6-Hydroxy-3-(3-O-β-D-glucopyranosyl- but-1-enyl)-2, 4,4-trimethyl-cyclohex-2-enone, along with two known glycosides. All the compounds had antibacterial activity, showing particularly potent activity against Staphylococcus aureus IFO 3060 and Bacillus subtilis.

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Author(s): B Wu WH Lin HY Gao L Zheng LJ Wu CS Kim

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