alexa Abstract | Free radical scavenging activity of leaves of <i>Alocasia indica</i> (Linn)

Indian Journal of Pharmaceutical Sciences
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Abstract

The free radical scavenging potential of the plant Alocasia indica (Linn.) was studied by using different antioxidant models of screening like scavenging of 1,1-diphenyl-2-picryl hydrazyl radical, nitric oxide radical, superoxide anion radical, hydroxyl radical, iron chelating activity, total antioxidant capacity, non-enzymatic glycosylation of haemoglobin, rapid screening for antioxidant compounds by thin layer chromatography. The hydroalcoholic extract at 1000 ΅g/ml showed maximum scavenging of superoxide radical (87.17) by riboflavin-NBT-system, followed by scavenging of stable radical 1,1-diphenyl-2-picryl hydrazyl radical (83.48%), nitric oxide radical (74.09%) hydroxyl radical (60.96%) at the same concentration. However the extract showed only moderate activity by iron chelation (68.26%). That could be due to higher phenolic content in the extract. This finding suggests that hydro alcoholic extract of A. indica possess potent in vitro antioxidant activity as compared to the standard ascorbic acid. The results justify the therapeutic applications of the plant in the indigenous system of medicine, augmenting its therapeutic value.

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Author(s): WA Mulla VR Salunkhe SB Kuchekar MN Qureshi

Keywords

Antioxidant, free radicals, Alocasia indicia, lipid peroxidation, ascorbic acid

 
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