alexa Abstract | FTIR molecular investigation on the concomitant effect of glycine and alcohol induced liver injury

Der Pharmacia Sinica
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access


Glycine is known to have a protective role against alcohol induced liver damage. The aim of our study was to evaluate the effect of glycine and alcohol treated albino rats, were analyzed for their lipid content and structural changes using Fourier transform infrared (FTIR) spectral and Light microscopic techniques, respectively. In the administering ethanol (5 g/kg body weight) every day to Wister albino rats for 45 days significantly elevated the lipid levels of liver was found to be increased as compared with the control rats. Simultaneous glycine supplementation (0.6 g/kg body weight) during 45 days of the experiment to rats administered alcohol reduced the lipid levels of tissue. As FTIR measurements are concerned, a vibrational assignment has been for the observed sub-band in the analysis in the C-H stretching region (3000-2800 cm-1) of samples has shown clear changes interpreted on the basis of the structural made in the same samples. Light microscopic examination of ethanol treated rat liver showed inflammatory cell infiltrates and fatty changes, which were reversed on treatment with glycine.

To read the full article Peer-reviewed Article PDF image

Author(s): R Selvaraju and K Subbashinidevi


Glycine, Ethanol, C-H stretching region, Infrared spectra, Light microscopy.

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

1-702-714-7001Extn: 9037

Business & Management Journals


1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version