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Herbal medicine is a very ancient art of healing. Antibiotics developed resistivity against many pathogens due to misuse of these agent that’s why antimicrobial potential is studied all over the world. The present study was conducted to analyze an in-vitro anti-bacterial activity of methanolic extract of Glycyrrhiza glabra and Azadirachta indica against two gram positive and three gram negative organism by using disk diffusion method at the concentrations of 20 ppm, 30 ppm and 40 ppm. The zones of inhibition were measured with mm scale and found in the range of 6 mm to 17 mm. The result reveals that methanolic extract of both plant posses anti-bacterial activity. These plant extracts may prove their promising role as antibiotics and may help to overcome the problem of resistivity against many pathogens. Moreover, anti-typhoid activity of these medicinal plants is promising to act as potential agent for treating typhoid fever from natural plant source.
Antibacterial activity, Glycyrrhiza glabra, Azadirachta indica, disc diffusion method and typhoid fever, General Medicine