alexa Abstract | Haematological profile shows that Inbred Sprague Dawley rats have exceptional promise for use in biomedical and pharmacological studies

Asian Journal of Biomedical and Pharmaceutical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Abstract

Background: Laboratory or model animals are used in research for cure and improvement of human and animal diseases. Rats particularly the inbred strains are now more widely used laboratory model especially in toxicology and for understanding the pathophysiology of diseases.
Aim: To determine the haematological indices of male and female inbred Sprague Dawley rats in health. Methods: An automated haematology analyzer was used to determine haematological indices of whole blood from individual in 20 each of male and female inbred Sprague Dawley rats. Mean, standard deviation, median interquartile range as well as minimum and maximum values for the haematological profile were calculated.
Findings: Statistically significant differences for total and differential white blood cells (WBC), red blood cells (RBC) and Haemoglobin (Hgb) levels were observed between male and female rats.
Conclusion: Data presented here would be useful as a reference for studies aimed at understanding the pathophysiology of diseases especially neoplasms and haematological disorders; as well as in evaluating alterations in blood parameters in relation to the pharmacological interventions and/or toxicological effects in inbred Sprague Dawley rats.

To read the full article Peer-reviewed Article PDF image

Author(s): Said NM Abiola O

Keywords

Disease pathophysiology, Haematological indices, Inbred Sprague Dawley rats, Pharmacological interventions, Toxicological effects

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords